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A Novel Way of Preventing Cancer: Anti-Angiogenesis

William Li presents a new way to think about treating cancer and other diseases: anti-angiogenesis, preventing the growth of blood vessels that feed a tumor. The crucial first (and best) step: Eating cancer-fighting foods that cut off the supply lines and beat cancer at its own game.


Beautiful Story…

From Daily Good

Don’t be afraid your life will end; be afraid that it will never begin. –Grace Hansen

Good News of the Day:
Every time 71-year-old Andy Mackie draws a breath, it is music to his ears, whether there’s a harmonica there or not. He’s just glad to be alive.”How are you still sitting here?” asked CBS News correspondent Steve Hartman. “I guess they don’t need a harmonica player in heaven yet,” Mackie said. Mackie, a Scottish-born retired horse trainer, lives in a camper in Northwest Washington State, even though technically, medically, he should have died a long time ago. After his ninth heart surgery, Mackie’s doctors had him on 15 different medicines. But the side effects made his life miserable. So one day he quit taking all 15 and decided to spend his final days doing something he always wanted to do. He used the money he would have spent on prescriptions to give away 300 harmonicas, with lessons. When he didn’t die the next month, he bought a few hundred more.  [ more ]

Be The Change:
Find a way to share an activity that you deeply enjoy with others.


Longevity Dicovery

From: Roger Greenway, ENN
Published December 28, 2009 02:00 PM

The University of Alabama at Birmingham (UAB ) has published an important research paper that shows a clear link between calorie intake and the lifespan of human cells.

Researchers from the have discovered that restricting consumption of glucose, the most common dietary sugar, can extend the life of healthy human-lung cells and speed the death of precancerous human-lung cells, reducing cancer’s spread and growth rate.

The research has wide-ranging potential in age-related science, including ways in which calorie-intake restriction can benefit longevity and help prevent diseases like cancer that have been linked to aging, said principal investigator Trygve Tollefsbol, Ph.D., D.O., a professor in the Department of Biology. “These results further verify the potential health benefits of controlling calorie intake.” Tollefsbol said. “Our research indicates that calorie reduction extends the lifespan of healthy human cells and aids the body’s natural ability to kill off cancer-forming cells.”

The UAB team conducted its tests by growing both healthy human-lung cells and precancerous human-lung cells in laboratory flasks. The flasks were provided either normal levels of glucose or significantly reduced amounts of the sugar compound, and the cells then were allowed to grow for a period of weeks. “In that time, we were able to track the cells’ ability to divide while also monitoring the number of surviving cells. The pattern that was revealed to us showed that restricted glucose levels led the healthy cells to grow longer than is typical and caused the precancerous cells to die off in large numbers,” Tollefsbol said.

In particular, the researchers found that two key genes were affected in the cellular response to decreased glucose consumption. The first gene, telomerase, encodes an important enzyme that allows cells to divide indefinitely. The second gene, p16, encodes a well known anti-cancer protein.
“Opposite effects were found for these genes in healthy cells versus precancerous cells. The healthy cells saw their telomerase rise and p16 decrease, which would explain the boost in healthy cell growth,” Tollefsbol said. “The gene reactions flipped in the precancerous cells with telomerase decreasing and the anti-cancer protein p16 increasing, which would explain why these cancer-forming cells died off in large numbers.”

The UAB research into the links between calorie intake, aging and the onset of diseases related to aging is thought to be a first of its kind given that it used the unique approach of testing human cells versus laboratory animals.

For more information: http://main.uab.edu/Sites/MediaRelations/articles/71819/